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Executive Summary Orforglipron (LY3502970) is the first oral, non-peptide, small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist to complete Phase 3 clinical development for the treatment of obesity and type 2 diabetes

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and TB-500 grabs onto a cell's internal scaffolding protein (actin) to help cells move quickly to where they're needed