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Further investigations are necessary to confirm the contribution of these processes to human disease and to evaluate potential therapeutic strategies targeting lactate transporters for neurological disorders

Key findings relevant to injection site safety: Injection site reactions were not significantly higher in retatrutide groups compared to placebo The most common injection site reactions were transient redness and mild discomfort No participants discontinued due to injection site reactions The overall safety profile was consistent with other GLP-1 receptor agonists The more recent TRIUMPH-4 phase 3 trial confirmed these safety findings in a larger population

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Jr., Bird, E.D