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Therefore, we tested mainly the following hypotheses: 1

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En contraste terico, los parches transdrmicos ofreceran ventajas potenciales como: Eliminacin del dolor y ansiedad asociados con inyecciones Posible mejora en la adherencia al tratamiento Liberacin continua y sostenida del medicamento Reduccin de picos y valles en concentraciones plasmticas No obstante, estas ventajas permanecen hipotticas hasta que se demuestre que los parches pueden alcanzar concentraciones teraputicas efectivas