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Future research integrating multi-omics approaches, such as metagenomics, metabolomics, and host transcriptomics, together with large-scale longitudinal studies and well-designed clinical trials, will be essential to clarify causal mechanisms and evaluate the long-term efficacy of microbiome-targeted interventions
One of the earliest biochemical changes seen in PD is a decrease in the levels of total GSH which occurs even before a reduction in mitochondrial complex 1 activity, dopamine levels, or the neurodegeneration that are all associated with the disease (Chinta et al., 2007)
These peptides showed no cytotoxic effect on mouse melanoma cells
Sci 21, 2061
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