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GLP-1s shouldnt be viewed as short-term fixes either, the editorial says

Abstract Parkinsons disease (PD), the second most common neurodegenerative disorder worldwide, features gradual loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) along with pathological -synuclein (-syn) aggregation

398 Disruption of the RAR-corepressor complex selectively activated CMA in retinal degeneration, conferring neuroprotection without broadly triggering macroautophagy

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Plain glutathione delivered to the plasma by precursors, liposomal products or intravenously must be broken down by enzymes to the basic amino acid components for absorption into the cell and require more energy expenditure to be re-constructed back to rGSH