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However, a phase 3 multi-center RCT of secukinumab in patients with psoriasis and coexisting NAFLD was early terminated, reportedly due to low rates of enrollment (ClinicalTrials.gov ID: NCT04237116)

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In the SURMOUNT-1 trial, people taking tirzepatide (Zepbound) lost an average of 22.5% of their body weight over 72 weeks