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Chakravertys word that the L-Carnitine administered to Farah fell within permissible limits

Oxid Med Cell Longev 2021(1):9932218

A proteome study of mouse cerebral cortex, hippocampus, and cerebellum found that the abundance of enzymes of the fatty acid beta-oxidation pathway, including acetyl-CoA acetyltransferase 1 (ACAT1) and acyl-CoA dehydrogenase medium chain (ACADM), declined with aging (Gostomska-Pampuch et al., 2021), while DR led to a 4-fold increase in ACAT1 persulfidation and a decrease in ACADM persulfidation in mouse brain (Bithi et al., 2021)

Wang et al., 2012

These alterations drive M1 polarization of hepatic macrophages via NLRP3 inflammasome activation, thereby reinforcing chronic inflammation (140, 141)