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Mitochondria are the powerhouses of our cells, responsible for generating ATP through a complex process called the electron transport chain

Adding BSO has been shown in the laboratory to increase the killing of cancer cells by melphalan

These changes resulted in elevated intracellular Fe 2+ levels and the downregulation of p-STAT3, SLC7A11, and GPX4 levels (57)

The majority of folate entering tissue cells is in the form of 5-methyl-THF monoglutamate or is quickly metabolized to this form, which has a low affinity for folylpolyglutamate synthetase 894

Their work showed that restoring MST1 expression activates p53, which subsequently phosphorylates Drp1 at Ser616 to facilitate mitochondrial fission while concurrently suppresses Parkin transcription (61)