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Unfortunately, the e-value is affected by the database size and several gaps and mismatches could be present without dramatically influencing the e-value

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Tirzepatide 5 mg showed an average weight loss of more than 5% of body weight at the median time of 16 weeks, while 10 and 15 mg took 12.4 weeks to show significant weight changes and glycemic control

These are symptoms of pernicious anemia, which occurs when the body doesnt have enough vitamin B12 to support healthy red blood cell production (NIH-b, 2021)