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Since IGF-1 encourages cell division, it could theoretically stimulate the growth of abnormal or precancerous cells

Chronic GH secretion suppresses the anti-lipolytic action of insulin and increases FFA flux into the systemic circulation, thereby promoting lipotoxicity, which causes pathophysiological problems, including insulin resistance [10]

As we age, declining growth hormone levels make fat loss increasingly difficult especially that persistent visceral fat around the midsection

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Membrane-mimicking phospholipids enhance intracellular delivery and retention