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1 This abrupt change came in response to raised concerns from certain investigations that documented an unexpected increase in cardiovascular (CV) risks for patients with T2DM randomized to active treatment arms of clinical trials

Direct effect on muscle growth Activation of satellite cells: After MSTN-IP7 blocks Myostatin, muscle stem cells can proliferate and differentiate normally, promoting the repair and regeneration of muscle fibers

Tirzepatide enhances both pathways, creating a more balanced and responsive metabolic environment

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