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When incubated with patulin, certain microorganisms including Saccharomyces cerevisiae (Moss and Long, 2002), Kodameae ohmeri (Dong et al., 2015), Gluconobacter oxydans (Ricelli et al., 2007), and Sporobolomyces accumulate E-and/or Z-ascladiol (Ianiri et al., 2013)

Mitochondrial DNA damage as driver of cellular outcomes

Unlike conventional pharmaceutical chelating agents (such as EDTA or DMPS), which can aggressively strip the body of essential minerals and cause severe nutritional deficiencies, MCP does not appear to alter the systemic levels or excretion of vital minerals like calcium, magnesium, iron, and zinc

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Reduced drug uptake serves as a primary line of defense, even before other resistance mechanisms develop