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Research has demonstrated that Dex can increase the expression of Nrf2 and its downstream proteins, NQO-1 and HO-1, in the brain tissue of TBI rats, thereby exerting neuroprotective effects [53]

GlyNAC supplementation also corrects GSH deficiency, OxS, and multiple aging hallmarks (mitochondrial dysfunction, abnormalities in mitophagy and nutrient sensing, and genomic damage) in vital organs such as the heart, liver and kidneys

Several factors can contribute to perceived treatment failure