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Moreover, ascorbate functions as a much more efficient superoxide scavenger than GSH and hences polices superoxide-dependent activities and signalling

Hypothelamic-Pituitary-Adrenal Axis Tumors of the cortisol-secreting cells of the adrenal cortex secrete excessive cortisol, resulting in excessive tissue protein degradation and muscle wasting Cushing's syndrome As a source of energy, amino acid carbon skeletons are directly oxidized, or, in the starved state, converted to glucose and ketone bodies, and then oxidized

These are often essential

2019 May;32(5):407-413

Kidney Int 91(2):387401 Su L et al (2019) Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury