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Patients commonly report sensations of heaviness, tightness, or discomfort in the affected limb

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Functionally, glutathione was essential for melatonin-mediated immunosuppression, as IKE co-treatment abolished the reductions in IL-5, IL-13, and IL-4 production observed with melatonin alone ( Figures 8FH )

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When you lose it, your baseline metabolic rate drops, your physical capacity decreases, and daily activities that previously felt easy start feeling harder