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STEP-2 (N=1,210 adults with type 2 diabetes) confirmed that even the 1.0 mg dose of semaglutide produces clinically significant metabolic changes within 8-12 weeks, which is well within the timeframe that ovulatory function may normalize in previously anovulatory women

Over the course of a year, half of the group was given the daily injectable GLP-1 medication liraglutide and the other half a placebo

The production of brain-derived neurotrophic factor (BDNF) in a CREB-dependent manner, which can prevent excitotoxic neuronal death by reducing the neurotoxic release of glutamate [60], has also been found to be increased following exenatide treatment in adult wild-type mice [97]

Before first use, unopened Ozempic (for diabetes) pens must be stored in a refrigerator at temperatures between 36F and 46F (2C to 8C)