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Further analysis of aged mice testes after FOXO4-DRI treatment revealed a reduction in interstitial SA--gal activity, along with decreased levels of senescence-associated proteins p53, p21, and p16

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As we age, natural GH production declines, leading to various signs of aging such as decreased muscle mass, increased body fat, and reduced bone health

doi: 10.2527/jas.2011-4682