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In mouse peritonitis, KPV reduced neutrophil accumulation and showed anti-inflammatory activity independent of classic melanocortin receptors, likely via inhibition of IL-1driven pathways rather than cAMP signalingevidence for KPVs MC-receptor-independent action
Age-matched mice or mice from same litters were randomly assigned to each group
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*Correspondence: Seppo Meri [email protected] Kalantar [email protected] This article was submitted to Inflammation, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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