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38 This pain commonly presents as spontaneous burning sensations in the feet, and patients may also report positive sensory symptoms such as brush-evoked allodynia (pain from normally non-painful stimuli) and paresthesias, which are often accompanied by sensory loss, leading patients to describe the paradox of their feet being continuously painful yet insensate to touch
The condition is named after the Spanish dermatologist, Juan Nicolau, who reported the first case in 1924 using bismuth salts to treat syphilis.[] Despite being a relatively rare condition, NS can erratically result in severe morbidity and mortality, making it necessary for healthcare professionals to be vigilant in recognizing and managing this condition
Sources Jastreboff, A.M., et al
The injection combines lipotropic substances
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