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In adipocytes, NNMT inhibition elevates NAD and SAM and suppresses de novo lipogenesis in a concentration-dependent manner, consistent with on-target activity [13]

10.1136/bmjopen-2019-033687 [DOI] [PMC free article] [PubMed] [Google Scholar] Saraswathy A

Any sign of adverse reactionagitation, headache, elevated blood pressuremeans the immediate cessation of the protocol

The authors concluded that the oral nutritional supplement containing collagen peptides reduced skin vulnerability in older adults and prevented skin tears with senile purpura [33]

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