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In addition, many natural substances (such as root and bark extracts) have not been thoroughly studied and may in fact contain hormonally active chemicals that are actually detrimental to male fertility

(5) Grabarevic Z, Tisljar M, Artukovic B, Bratulic M, Dzaja P, Seiwerth S, Sikiric P, Peric J, Geres D, Kos J

HUBERMAN: So again, you want to avoid food in the hour and a half, probably two hours before taking them, and certainly in the half hour or longer after, which is why most people take them right before going to sleep, and add or augment that big growth hormone pulse that occurs in the early part of the night

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L D Juby, J Rothwell, A T Axon