This activated AMPK phosphorylates PD-L1 on Ser283, which interrupts its association with CMTM4 and results in PD-L1 degradation
Neurochem Res 37:27062714 Galasko DR, Peskind E, Clark CM, Quinn JF, Ringman JM, Jicha GA, Cotman C, Cottrell B, Montine TJ, Thomas RG, Aisen P, Alzheimer's Disease Cooperative S (2012) Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures
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