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Understanding this nuanced risk-benefit profile enables informed shared decision-making between healthcare providers and patients considering GLP-1 therapy

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This article is part of the PlexusDx Education Hub, where we publish evidence-based guidance on GLP-1 therapies, weight management protocols, and the genetic factors behind every metabolic decision

Purpose-built for physicians Cases of acute cholecystitis linked to GLP-1 receptor agonist use in US Researchers have found 36 cases of acute cholecystitis associated with the use of GLP-1 receptor agonists in the U.S., according to findings from the FDA Adverse Event Reporting System published in JAMA Internal Medicine

They have also identified a plethora of pathological molecular and neuronal phenotypes observed in schizophrenia patients, confirming the translational significance of these pre-clinical models [6, 7]