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MAO-B MAO-B (Monoamine Oxidase B) is highly and selectively expressed in astrocytes, and its upregulation in reactive states exhibits greater astrocyte specificity than that of TSPO

Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1, as well as pattern recognition receptor proteins like CRP (170, 261267)

The molecule plays a direct role in brain energy and cognitive function

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Structure of a yeast catalytic step I spliceosome at 3.4 A resolution