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Additionally, IGF-1 LR3 is investigated for its interaction with insulin-like growth factor binding proteins (IGFBPs), which regulate peptide availability and receptor engagement

This work was supported by NIH grants R01GM111730 (J.H.H.) and R01GM130995 (R.Z.), Department of Defense Peer Reviewed Medical Research Program Discovery Award W81XWH2010086 (J.H.H.), the Bakar Fellows program (J.H.H.), the Pew-Stewart Scholarship for Cancer Research and Damon Runyon-Rachleff Innovation Award (R.Z.), a postdoctoral fellowship from the Association for Frontotemporal Degeneration (M.-Y.S.) and an EMBO Long-Term Fellowship (S.A.F.)

PMCID: PMC3728035 ) Acknowledgements Figure 1 was created with Biorender.com

It is used in lab research to study brain health and cell growth in a safe, controlled manner

Nausea or vomiting risk in the same tool stretched from 5% to 78%, showing how wide the gap can be