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151 In rat NP cells, 152 GDF5 overexpression inhibited the secretion of TNF, IL1, PGE2, and NO in culture medium induced by LPS, inhibited the decrease in matrix production, including collagen II and aggrecan, and prevented NFB activation induced by LPS

Nature 412 , 549553 (2001)

tb in T2DM Subjects Levels of cytokines: IL-6, IL-10, IFN- and TNF- were quantified from the supernatants of in vitro granulomas generated from PBMCs isolated from T2DM subjects at pre- and post- L-GSH/or placebo supplementation

Homma K, Fujisawa T, Tsuburaya N, Yamaguchi N, Kadowaki H, Takeda K et al (2013) SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency

While these medicationsincluding semaglutide (Ozempic, Wegovy, Rybelsus) and liraglutide (Victoza, Saxenda)are FDA-approved only for metabolic conditions, emerging research explores whether their anti-inflammatory properties and effects on brain glucose metabolism might slow cognitive decline