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10.3389/fendo.2022.869951 103 MatsuokaT.KawashimaS.MiyatsukaT.SasakiS.ShimoN.KatakamiN.et al (2017)
This link operates through complex molecular pathways, prominently featuring FoxO1/LEPR and JAK/STAT3 signaling, and possibly involving Cdc42
"The field now needs to focus on understanding those processes in much greater detail and developing treatments that can be used together to tackle the disease from multiple angles." She added that the growing use of GLP-1 medicines through private prescriptions, largely for weight loss, offers an opportunity to gather better real-world data on their longer-term effects
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