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This extends the total time to reach the maintenance dose but substantially reduces the likelihood of side effects that cause discontinuation

Storage conditions must be followed exactly as stated on the IMP label or clinical trial protocol, which typically specifies refrigeration at 2C to 8C

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In this capacity, it may counter metabolic disease symptoms

After a closed head injury, ApoE / mice exhibit elevated levels of iron in their brains, suggesting that ApoE / deficiency may increase the risk of oxidative damage to hippocampal tissue ( In vitro studies show that upregulating sestrin2 decreases type I/II collagen and KEAP1 mRNA expression while increasing GPX4 and Nrf2 mRNA levels