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15 By means of its neuroprotective action and central anti-nociceptive properties, ALC provided a significant pain reduction, as measured by NPSI questionnaire

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Results: Incidence rates for pancreatitis (adjusted HR [aHR] 9.1, 95% confidence interval [CI] 1.25-66), bowel obstruction (aHR 4.2, 95% CI 1.02-17.4), and gastroparesis (aHR 3.7, 95% CI 1.2-11.9) were significantly higher among users of GLP-1 receptor agonists compared to buproprion-naltrexone users

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