Following 24-week treatment, response thresholds to four different stimuli were tested and found to be lower in diabetic rats than in normal rats
Molecular Medicine Reports, 19 (2), 783791
In preclinical models of NASH, the administration of AC3174, an analogue of exenatide, led to significant reductions in body weight, LFC, and levels of plasma alanine aminotransferase (ALT) and triglyceride [24]
PGC-1 is a central regulator of transcriptionally governing mitochondrial biogenesis by activating several transcription factors such as NRF1, NRF2, and PPAR [322]
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