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The C5 domain of nocardicin NRPS (NocB) not only fulfills its canonical function by forming the corresponding amide bond in the growing peptide chain, but also mediates cyclization of the beta lactam ring 29

Such reduction might be due to the increased expression of the negative regulators, such as SOCS

Many patients follow an organised care plan that includes both the GP and specialist

Dermal melanocytosis may be confused with child abuse and rarely is associated with inborn errors of metabolism

Why weight management is key for heart health Carrying extra weight, despite having healthy blood pressure, blood glucose, and cholesterol levels, can increase the likelihood of having a heart attack by up to 28%