Not because the compound does not work, it does, but because they are treating a systemic repair problem with a localised tool and expecting that to be enough
A numerical increase in thyroid C-cell carcinomas was observed in rats at 400 mcg/kg/day, resulting in systemic exposures that are 56-times the human exposure achieved at 20 mcg/day based on plasma AUC
Notably, T2DM is closely associated with various neurodegenerative conditions ranging from mild cognitive impairment (MCI) to dementia
This is not a one size fits all scenario and reflecting No decision about me without me (Department of Health, 2012), the same considerations need to be applied in the PwDs decision to potentially not engage with this group GLP-1 RA start and opt for an individual one- to-one GLP-1 RA start instead.
They're everywhere in ads, on TikTok, in celebrity interviews, and even in group chats