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doi: 10.1159/000341454 37 LiN.ZhaoY.YueY.ChenL.YaoZ.NiuW

13 This study found that rats treated with exendin-4 had increased endothelial progenitor cells and protein levels of vascular endothelial growth factor receptor-2 (VEGF R2), phosphorylated endothelial nitric oxide synthase (eNOS), matrix metalloproteinase-2 (MMP-2), and transforming growth factor- (TGF-)

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Moreover, semaglutide and other GLP-1 receptor agonists have been shown to reduce the risk of adverse cardiovascular events in patients with diabetes, but they had not been tested for this purpose in patients with no history of diabetes

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