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Additionally, TPZ enhances fluorescent staining of ferrous ions while reducing SLC7A11 and GPX4 expression, thus promoting ferroptosis and hindering the proliferation and migration of osteosarcoma cells ( Pientzehuang (PZH) demonstrates inhibitory effects on the diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) model in rats

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Moreover, free phenolic extract from rape BP possesses higher capabilities to defend body cells from aberrant melanogenesis than bound phenolic extract via the suppression of microphthalmia-associated transcription factor (MITF) and downregulation of cyclic adenosine monophosphate (cyclic adenosine monophosphate) while preventing the anti-tyrosinase and antioxidant pathways in vitro (22)