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Decreased motility of the lower esophageal sphincter in a rat model of gastroesophageal reflux disease may be mediated by reductions of serotonin and acetylcholine signaling

In summary, FOXO4-DRI exerts its anti-aging effects by inhibiting the binding of FOXO4 to P53, promoting P53 phosphorylation, and facilitating the translocation of p-P53 from the nucleus to the cytoplasm for its functional role

Obesity and Lipotoxicity, 2024: pp

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"We are seeing this increase in calls to poison control centers, either for an overdose or for adverse events, and in some cases, that's leading to nausea, vomiting, dehydration, low blood sugar, causing people to have to go to the emergency room and in some cases, be hospitalized," said Parekh