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An American Diabetes Association study found that, while people with prediabetes typically incur a few hundred dollars in additional medical costs each year, those with blood sugar levels that have progressed to the diabetic range could face several thousand dollars more in annual expenses as much as 25 times higher

Desai, MD, a dermatologist and assistant professor at the University of Texas Southwestern Medical Center in Dallas

The mechanism may involve changes in bile composition or direct effects on gallbladder motility

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Also, high levels were associated with worse outcomes in people with primary sclerosing cholangitis, an immune-related disease of the liver [34]