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Robust markers of cellular senescence including Cdkn2a, Cdkn1a and SASP (i.e., Tnfa, Il1b, Clxcl1, etc.,)

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Visible results, such as reduced shedding and increased vellus hair (peach fuzz), may be noticeable within 2-3 months, but significant improvements in density and thickness often take 4-6 months of consistent daily application