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In those cases: Vitamin C is absorbed by immune cells and tissues

5 Application of oxidative stress in IBD therapeutics Oxidative/nitrosative stress is a significant pathophysiologic aspect involved in the development and course of IBD

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For example, spray-dried alginate/gum arabic microcapsules loaded with vitamin C increased its decomposition temperature to 188 C, well above typical food processing temperatures (95)

To functionally confirm that aggressive TNBC cells undergo ferroptosis, we exposed the ferroptosis-sensitive 4T1, 4T07, D2A1-m1, and D2A1-m2 cells to RSL3 or erastin together with either the radical-trapping antioxidant ferrostatin-1 (Fer-1), the iron chelator agent deferoxamine (DFOM) or an ACSL4 inhibitor (ACSL4i, Fig