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The pills haven't been compared head-to-head in a clinical trial, but in separate studies, the Wegovy pill showed average weight loss of 14% over 64 weeks, compared with 2% for a placebo, while orforglipron showed 11% weight loss over 72 weeks on its highest dose, compared with 2% for the placebo group

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Individuals Struggling With Stubborn Fat Those who have difficulty losing fat despite consistent diet and exercise may benefit from targeted metabolic support

This is a newly approved use for the drug as of

Instead of a 20-screen written questionnaire followed by an async provider review, the patient picks a named clinician and an explicit appointment slot, pays the $99 visit fee, and then has a real live conversation with a board-certified physician who takes the history, asks the safety questions, and decides on a treatment plan in real time