Oocyte-derived E-cadherin acts as a multiple functional factor maintaining the primordial follicle pool in mice
The small sample size was an immediate red flag for many, as was the strikingly fast turnaround from submission of the initial manuscript to online publication with a submission date of March 16, it appeared that the entire publication process must have been completed within just four days, which anyone whos ever tried to get a paper published will struggle to believe
So, we recommend using SL vitamin B12 rather than oral and IM, especially in patients who do not tolerate IM injection and patients who need prolonged vitamin B12 supplementation, such as patients with long-term metformin use and patients with pernicious anemia or with gastro-duodenal resection [51,52,53,54]
This is also the structure Novo Nordisk's own investigational semaglutide+cagrilintide combination used in REDEFINE 1 (Garvey et al., NEJM 2025) both components stepped in parallel through a 16-week ramp rather than introduced together at maintenance
Prothymosin was likely the first actual IDP characterized by SAXS (Gast et al., 1995
