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TB-500 is a synthetic fragment of thymosin beta-4 (residues 1723, sequence Ac-LKKTETQ) studied for its role in actin sequestration and cytoskeletal organization specifically the regulation of G-actin to F-actin polymerization balance that governs cell morphology and migration

Results were presented at the 2024 AASLD Liver Meeting and published in The New England Journal of Medicine

PMID: 27 FinotelloFMayerCPlattnerCLaschoberGRiederDHacklHet al

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After that, most stable patients need labs every 6 months, though people with diabetes, kidney disease, or liver issues may need checks every 3 months