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In vitro studies have shown increased collagen I and III gene expression and protein production in fibroblast cultures treated with GHK-Cu, with effects observed across a range of nanomolar to low micromolar concentrations

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This means they can penetrate the blood-brain (or blood-SCF) barrier and reach neurons directly, enabling the drug to exhibit organ-specific combined effects in the brain

The gap is in large-scale human randomised controlled trials, which have not yet been conducted

When the body is overwhelmed or unbalanced, this translates to its largest organ, which is the skin