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Contact your provider if you observe: Resting heart rate consistently above 100 BPM An increase of 10 bpm or more from your baseline that persists New or worsening: Palpitations Chest discomfort Dizziness Shortness of breath What To Tell Your Prescriber Before Beginning Treatment People with the following conditions should notify their prescriber before starting semaglutide: Tell your clinician about any history of: Heart disease Heart failure Arrhythmia Fainting Thyroid cancer Pancreatitis Digestive motility problems Kidney disease Eye disease All current medications and supplements Also mention lifestyle factors like caffeine and stimulant use