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How blockbuster weight-loss drugs differ GLP-1 agonists drugs that mimic a natural hormone called glucagon-like peptide-1 have transformed the treatment of obesity and diabetes, and seem to hold promise for other conditions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Page M.J., McKenzie J.E., Bossuyt P.M., Boutron I., Hoffmann T.C., Mulrow C.D., Shamseer L., Tetzlaff J.M., Akl E.A., Brennan S.E., et al

A weight loss of at least 10% was achieved by 22.6% of patients in the twice-daily group, 17.4% in the once-daily group, and 9.7% in the placebo group

Medications most commonly affected include oral contraceptives, thyroid medications (levothyroxine), blood pressure medications, and some psychiatric medications