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Neo November 12, 2023, 1:52pm #11 Hi @tongMD , great to see your thoughtful and rich entry Do you have any perspective on how the increase in insulin from these GLP-1 drugs might impact an optimal longevity phenotype

Its not about deprivation

Notably, many confounding factors like medical treatment, drug intake, and dental plaque existence were not taken into consideration, which could reduce the credibility of the experiment

When individuals are found to be deficient in NAD+, they may be prescribed NAD injection supplements to increase their bodys levels

Furthermore, CaMKII autophosphorylation is detectable during wake (Vyazovskiy et al., 2008) and early sleep following experience-dependent plasticity induction in the cortex (Young et al., 2006