Wiley Encyclopedia of Clinical Trials
Nervous system disorders Uncommon: Headache Not known: Convulsions*, Dizziness Heart disease Not known: Palpitations Vascular pathologies Uncommon: Hypertension, Hypotension Respiratory, thoracic and mediastinal pathologies Not known: Dyspnea Gastrointestinal disorders Common: Vomiting, Nausea, Diarrhea, Abdominal pain Uncommon: Dysgeusia, Dyspepsia, Dry mouth Skin and subcutaneous tissue disorders Uncommon: Abnormal skin odor ** Not known: Itching, Skin rash Musculoskeletal and connective tissue disorders Uncommon: Muscle spasms Not known: Myasthenia***, Muscle tension Systemic disorders and conditions related to the administration site Uncommon: Chest pain, Feeling abnormal, Pyrexia, Injection site reaction**** Diagnostic tests Uncommon: Increased blood pressure Very rare: Increased INR*****
49 Cystic fibrosis
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Synthesis of EC 1665 D-Glu D-Glu D-Cys EC1579 (15mg, l.Oeq) was dissolved in degassed (Ar bubbling) 20mM P0 4 pH7 buffer (2.0mL) and added dropwise to a stirring solution of EC0564 (10.5mg, l.Oeq) in dry dimethylsulfoxide (4.0mL, Aldrich) at room temperature with Ar bubbling