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Discussion Metformin has garnered significant attention for its potential therapeutic effects on various diseases, including IIRI, although the precise underlying mechanisms remain to be elucidated [15]

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7:110 Saad MA, Abdelsalam RM, Kenawy SA, Attia AS (2015) Montelukast, a cysteinyl leukotriene receptor-1 antagonist protects against hippocampal injury induced by transient global cerebral ischemia and reperfusion in rats