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Thirteen-week inhalation toxicity of 2- and 4-chloronitrobenzene in F344/N rats and B6C3F1 mice

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Progress should be tracked with symptoms and function changes

What has changed is not the feasibility of developing drugs without complete biological knowledge, but the expectation that developers be transparent about what is and is not known, and that uncertainty be actively managed rather than minimized (ICH E9 guidance

WO2003045373A1 - Use of propionyl l-carnitine or one of its pharmacologically acceptable salts for the preparation of a medicine for the treatment of la peyronie's disease - Google Patents Use of propionyl l-carnitine or one of its pharmacologically acceptable salts for the preparation of a medicine for the treatment of la peyronie's disease Download PDF Info Publication number WO2003045373A1 WO2003045373A1 PCT/IT2002/000745 IT0200745W WO03045373A1 WO 2003045373 A1 WO2003045373 A1 WO 2003045373A1 IT 0200745 W IT0200745 W IT 0200745W WO 03045373 A1 WO03045373 A1 WO 03045373A1 Authority WO WIPO (PCT) Prior art keywords disease carnitine peyronie propionyl medicine Prior art date Legal status (The legal status is an assumption and is not a legal conclusion