glp-1 and insulin GLP-1-based therapies for type 2 diabetes: from single, dual triple agonists to endogenous production and L-cell differentiation | Diabetology & Metabolic Syndrome GLP-1 Receptor Agonists Explained for

Type 2 Diabetes Focus# Recommendation : Tirzepatide Reason : Tirzepatide has 5 SURPASS T2D trials, FDA approval for diabetes (Mounjaro), and demonstrated superiority over semaglutide in SURPASS-2

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The standard titration schedule increases the dose every four weeks, and patients may experience transient symptoms as their body adjusts to higher medication levels

Because of this, I recommend any patient who is symptomatic and has suboptimal levels of vitamin B12 (as defined above) consider a trial of sublingual B12