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[PubMed] [Google Scholar] 78.Xuan B., Zhou Y.H., Li N., Min Z.D., Chiou G.C

It acts as a mitochondrial messenger that communicates with the nucleus to maintain cellular homeostasis, making it a promising target for research on metabolic health, exercise performance, and healthy aging 1-4

Specifically, SP and SP@M increased the LC3-mediated autophagy as well as strengthened the ubiquitin-mediated proteasomal degradation toward KEAP1 (Figs

It's based on Nobel Prize-winning research

Co-localization studies revealed that many of the DNA damage sites that are occupied by -H2AX did not co-localize with pNPM1 to efficiently repair all the damaged sites, which could in turn lead to tumor cell death